Molecular Details
DICL_CP_0337832
- 3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0337832
PubChem CID
Molecular Formula
C24H27N Molecular Weight
329.487 g/mol
Synonyms/Alias
[PRENYLAMINE; 390-64-7; Segontin; DL-Prenylamine; Hostaginan; Bismethin; Falliocor; Synadrin; Valecor; Corpax; Elecor; Prenilamina; Prenylamine (vasodilator); Sandoz 13-194; N-(3;3-Diphenylpropyl)-alp...
InChI Key
IFFPICMESYHZPQ-UHFFFAOYSA-N
InChI
InChI=1S/C24H27N/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,2...
IUPAC Name
3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine
CAS Number
390-64-7
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
52 54 0 0 0 0 0 0 0 0999 V2000
3.0456 1.4778 -1.4941 C 0 0 0 0 0 0 0 0 0 0 0 0
2.0405 0.9024 -0.4794 C 0 0 0 0 0 0 0 0 0 0 0 0
2.6472 0.834...
Experimental Data
Activity Data
Target Ion Channel
G protein activated inward rectifier potassium channel 1/2
Uniprot Accession Number
Function
Activator
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
EC50: 3070 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
Not mention mV
Temperature
20–23 °C
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
25
Rotatable Bonds
8
logP
5.4294
Complexity
106.9547
TPSA (Ų)
12.03
H-Bond Donors
1
H-Bond Acceptors
1
Ring Count
3